Employing solitary-molecule optical and AFM imaging and force-spectroscopy procedures, we find to unravel the mechanistic facets of the structure and dynamics of chromosomes. Our investigate passions contain:

Human Rad51 filaments on double- and one-stranded DNA: correlating standard and irregular forms with recombination operate.

‘It was simply just a subject of selecting up a e-book on cell biology and beginning to go through. I had originate from a planet of ultra-superior vacuums, cryostats and quantum phenomena, and now I used to be Operating at home temperature with molecular biology kits.

Non-equilibrium folding of personal DNA molecules recaptured around one thousand instances within a sound state nanopore

De sterke polarisatie in de discussie rond schepping/evolutie en meer algemeen rond geloof/wetenschap lijkt helaas geen eind te kennen. Toch is er wel degelijk een heilzame middenweg, maar deze krijgt over het algemeen weinig aandacht. Dit boek kan hier wellicht verandering in brengen. Wie de geschiedenis van de relatie tussen geloof en wetenschap in duikt, komt tot verrassende inzichten. De moderne mens leeft met veel stereotypen die historisch niet verantwoord blijken te zijn. Afgezaagde typeringen als ‘Vroeger dachten we dat de

SMC complexes can move Bodily roadblocks bigger than their ring size, indicating a nontopological mechanism for DNA loop extrusion

Considering the fact that 2000 he moved to solitary-molecule biophysics and nanobiology, with analysis from DNA supercoiling research of nucleosomes and DNA repair proteins to DNA translocation as a result of nanopores. A short while ago his exploration has focused on studying mobile division with micro organism on chip, although his greatest desire is while in the path of realizing artificial cells.

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Dekker began his research on one carbon nanotubes in 1993 when he put in place a fresh line of research to check electrical transport through one natural molecules between nanoelectrodes. In 1996 a breakthrough was understood with carbon nanotubes. This was attained in a collaboration While using the group of Nobel laureate Richard Smalley. STM and nanolithography techniques ended up ceesdekker.net used to reveal that these nanotubes are quantum wires at The only-molecule amount, with fantastic physical Attributes.

[fourteen] In 2005 Dekker grew to become linked to Netherlands-vast conversations about Intelligent Style and design, a movement that he has due to the fact Obviously distanced himself from. Dekker advocates that science and faith usually are not in opposition but is usually harmonized.

Nanoscientist Cees Dekker can be an amiable and flamboyant person who seems Substantially more youthful compared to 62 years he basically is – stylish glasses, psychedelic shirt, partaking smile – although not one particular to waste time. He requires his time, but not more than important.

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2013, controlled shaping of Are living bacterial cells into arbitrary designs; and discovery of spontaneous fluctuations in the handedness of histone tetrasomes